15 Best Comfort Food Casserole Recipes

Chicken and Rice Casserole
A classic comfort food, Chicken and Rice Casserole combines simple ingredients to make a deliciously warming meal.
Ingredients:
- 2 cups cooked chicken, shredded
- 1 cup white rice
- 1 can (10.5 oz) cream of mushroom soup
- 1 cup chicken broth
- 1 cup mixed vegetables
- 1 cup shredded cheddar cheese
- Salt and pepper to taste
Cooking method:
- Preheat your oven to 350°F (175°C).
- In a large mixing bowl, combine the chicken, rice, cream of mushroom soup, chicken broth, and mixed vegetables.
- Season with salt and pepper, then mix well.
- Transfer the mixture into a greased casserole dish.
- Sprinkle shredded cheddar cheese over the top.
- Bake in the preheated oven for 25-30 minutes, or until the cheese is bubbly and golden.
- Let cool slightly before serving.
Cheesy Broccoli and Quinoa Casserole
This Cheesy Broccoli and Quinoa Casserole is a nutritious twist, adding whole grains and veggies without compromising on the creamy, cheesy goodness.

Ingredients:
- 2 cups cooked quinoa
- 1 ½ cups broccoli florets
- 1 cup milk
- 2 cups shredded cheddar cheese
- 1 teaspoon garlic powder
- Salt and pepper to taste
Cooking method:
- Preheat oven to 375°F (190°C).
- Steam broccoli until just tender.
- In a large bowl, combine quinoa, broccoli, milk, cheddar cheese, and garlic powder. Season with salt and pepper.
- Spread the mixture in a greased baking dish.
- Bake for 20 minutes, or until the cheese is melted and bubbly.
- Allow to cool slightly before serving.
Beef and Potato Casserole
A hearty Beef and Potato Casserole is perfect for any meat and potato lover looking for a comforting dish.
Ingredients:
- 1 lb ground beef
- 4 cups thinly sliced potatoes
- 1 onion, chopped
- 1 can (10.5 oz) cream of mushroom soup
- 1 cup shredded mozzarella cheese
- Salt and pepper to taste

Cooking method:
- Preheat oven to 375°F (190°C).
- In a skillet, cook ground beef and onions until the beef is browned.
- Drain excess fat and season with salt and pepper.
- Layer potatoes, beef mixture, and cream of mushroom soup in a greased casserole dish.
- Top with shredded mozzarella cheese.
- Cover and bake for 45 minutes, then uncover and bake for an additional 15 minutes until cheese is golden.
- Allow to rest before serving.
Tuna Noodle Casserole
Revamp a classic with this Tuna Noodle Casserole, a dish that is as easy to make as it is comforting.
Ingredients:
- 2 cups egg noodles
- 1 can (6 oz) tuna, drained
- 1 can (10.5 oz) cream of celery soup
- 1 cup frozen peas
- ½ cup milk
- 1 cup bread crumbs
- 1 cup shredded cheddar cheese
Cooking method:
- Preheat oven to 350°F (175°C).
- Cook egg noodles according to package instructions; drain.
- In a large bowl, combine noodles, tuna, cream of celery soup, peas, and milk.
- Transfer to a greased casserole dish.
- Top with bread crumbs and cheddar cheese.
- Bake for 25-30 minutes, or until bubbly and golden.
- Let it sit for a few minutes before serving.
Vegetarian Enchilada Casserole
This Vegetarian Enchilada Casserole delivers tasty Mexican flavors without the meat.
Ingredients:
- 8 corn tortillas
- 1 can (15 oz) black beans, drained and rinsed
- 1 can (10 oz) enchilada sauce
- 1 cup corn
- 1 cup shredded Monterey Jack cheese
- 1 teaspoon cumin
Cooking method:
- Preheat oven to 375°F (190°C).
- Layer half of the tortillas on the bottom of a greased baking dish.
- In a bowl, mix beans, corn, and cumin.
- Spread half of the enchilada sauce over the tortillas, then add the bean mixture.
- Top with half of the cheese and repeat layers.
- Bake for 20-25 minutes, until cheese is bubbly.
- Cool slightly before serving.
Zucchini and Cheese Casserole
This Zucchini and Cheese Casserole is a light and savory dish that's great for any time of the year.
Ingredients:
- 3 zucchinis, sliced
- 1 onion, chopped
- 1 cup ricotta cheese
- 2 eggs, beaten
- 1 cup grated Parmesan cheese
- Salt and pepper to taste
Cooking method:
- Preheat oven to 350°F (175°C).
- In a skillet, sauté onion until translucent. Add zucchini and cook for 5 minutes.
- In a bowl, combine ricotta cheese, eggs, and Parmesan cheese.
- Stir in cooked vegetables and mix well.
- Pour the mixture into a greased casserole dish.
- Bake for 30-35 minutes, until the top is golden.
- Allow to cool before serving.
Sausage and Pepperoni Pizza Casserole
This Sausage and Pepperoni Pizza Casserole captures the flavor of your favorite pizza in casserole form.
Ingredients:
- 1 lb sausage
- 1 cup sliced pepperoni
- 2 cups pasta (penne or rigatoni)
- 1 jar (24 oz) pasta sauce
- 2 cups mozzarella cheese
- 1 teaspoon Italian seasoning
Cooking method:
- Preheat oven to 375°F (190°C).
- Cook pasta according to package instructions.
- In a skillet, brown sausage, then drain fat.
- In a large bowl, combine pasta, sausage, pepperoni, pasta sauce, and Italian seasoning.
- Pour into a greased baking dish and top with mozzarella cheese.
- Bake for 25-30 minutes until cheese is bubbly and browned.
- Cool slightly before serving.
Spinach and Artichoke Casserole
Inspired by the classic dip, this Spinach and Artichoke Casserole is creamy, cheesy, and packed with flavor.
Ingredients:
- 2 cups cooked spinach, drained
- 1 can (14 oz) artichoke hearts, chopped
- 1 cup sour cream
- 1 cup mayonnaise
- 1 cup Parmesan cheese
- 1 tsp garlic powder
Cooking method:
- Preheat oven to 350°F (175°C).
- In a bowl, mix spinach, artichoke hearts, sour cream, mayonnaise, Parmesan cheese, and garlic powder.
- Spread mixture into a greased baking dish.
- Bake for 20-25 minutes until golden.
- Allow to cool slightly before serving.
Macaroni and Cheese Casserole
This Macaroni and Cheese Casserole is a creamy, cheesy delight that is perfect for indulging on a cozy night in.
Ingredients:
- 2 cups elbow macaroni
- 2 cups milk
- 2 cups shredded cheddar cheese
- ½ cup breadcrumbs
- ¼ cup butter
- Salt and pepper to taste
Cooking method:
- Preheat oven to 350°F (175°C).
- Cook macaroni according to package directions and drain.
- In a saucepan, melt butter, add milk, and stir in cheese until melted.
- Combine cheese sauce with macaroni in a greased casserole dish.
- Top with breadcrumbs.
- Bake for 25-30 minutes until golden and bubbly.
- Let it cool before serving.
Sweet Potato and Black Bean Casserole
Combining sweet and savory flavors, Sweet Potato and Black Bean Casserole is a warm, hearty dish perfect for fall.
Ingredients:
- 3 large sweet potatoes, peeled and cubed
- 1 can (15 oz) black beans, drained and rinsed
- 1 cup salsa
- 1 cup shredded cheddar cheese
- 1 teaspoon chili powder
Cooking method:
- Preheat oven to 400°F (200°C).
- Boil sweet potatoes until tender, drain, and mash.
- In a bowl, mix mashed sweet potatoes, black beans, salsa, and chili powder.
- Spread mixture into a greased casserole dish.
- Top with cheddar cheese.
- Bake for 20-25 minutes, or until cheese is melted and bubbly.
- Cool slightly before serving.